Mouse Monoclonal antibody to CalmodulinCalmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.
Immunogen
Calmodulin purified from Dictyostelium discoideum.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6D4
Host Species
Mouse
Tested Applications
ELISAICC/IFWB
For ICC/IF: Use at a concentration of 1-2 µg/ml. :
Species Reactivity
HumanMouseChickenRatBacteriaBovine
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PHKD CALML2 P62158 CAMI Calmodulin 801 CALM1 114180 DD132
Target
Calmodulin
Application
Application
Western blot of purified calmodulin using
Application Notes
For ICC/IF: Use at a concentration of 1-2 µg/ml. :
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.