| Product description |
Mouse monoclonal [CALP] to CalponinCalponin, a calmodulin, binds tropomyosin and F-actin and is thought to be involved in the regulation of smooth muscle contraction. The expression of calponin is restricted to smooth muscle cells and is a marker of the differentiated contractile phenotype of developing smooth muscle. Two isoforms of calponin exist whose molecular weights are 34 kD and 29 kD. Expression of the 29 kD form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelialcells from benign and malignant breast lesions. |