Application
Western blot analysis of CAMK2A (arrow) using rabbit polyclonal CAMK2A Antibody (C-term E370) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK2A gene (Lane 2).Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Western blot analysis of anti-CAMK2A Antibody (C-term E370) in 293 cell line lysates (35ug/lane). CAMK2A(arrow) was detected using the purified Pab.| Product Name | CaMKII alpha antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CAMKII alphaThe product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide between 361~391 amino acids from the C-terminal region of human CAMK2A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| ELISA: Use at 1:1,000: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | Calcium/calmodulindependent protein kinase type II al CaMkinase II alpha chain Calcium/calmodulindependent protein kinase type II alpha chain CaMKII subunit alpha CaMK-II subunit alpha EC2.7.11.17 Calcium/calmodulin-dependent protein kinase type II a |
|---|---|
| Target | CAMKII alpha |
| Molecular Weight(MW) | 54.03 kDa (note) |
| Cellular Localization | Postsynaptic lipid rafts. |
Application
Western blot analysis of CAMK2A (arrow) using rabbit polyclonal CAMK2A Antibody (C-term E370) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK2A gene (Lane 2).
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Western blot analysis of anti-CAMK2A Antibody (C-term E370) in 293 cell line lysates (35ug/lane). CAMK2A(arrow) was detected using the purified Pab.| Application Notes | ELISA: Use at 1:1,000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.09% (W/V) sodium azide |
