| Product Name | Cardiac Troponin C antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [12G3] to cardiac Troponin CTroponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. |
| Immunogen | Human cardiac troponin C. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 12G3 |
| Host Species | Mouse |
| Tested Applications | PurifyELISAWB |
| AP: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 19 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | 7134 TNNC TNC Cardiac Troponin C TNNC1 191040 P63316 |
|---|---|
| Target | Cardiac Troponin C |
| Application Notes | AP: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 19 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4 |
