| Product Name | Cardiac Troponin I antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [267] to cardiac Troponin ITroponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATP-ase activity of acto-myosin and TnT and TnI are presented in cardiac muscles in different forms than in skeletal muscles. Only one tissue-specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium. |
| Immunogen | Synthetic peptide (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | 267 |
| Host Species | Mouse |
| Tested Applications | EIAELISA |
| M18 (GTX10236) + 560 (GTX38795) mixture for capture and 19C7 (GTX28289) + 267 (this antibody) mixture for detection : |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | 7137 CMH7 TNNI3 Cardiac Troponin I cTnI 115210 P19429 TNNC1 MGC116817 |
|---|---|
| Target | Cardiac Troponin I |
| Tissue Specificity | No cross reactivity with skeletal forms of the protein as well as with cTnT and TnC. |
| Application Notes | M18 (GTX10236) + 560 (GTX38795) mixture for capture and 19C7 (GTX28289) + 267 (this antibody) mixture for detection : |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: PBS |
