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Cardiac Troponin I antibody

Catalog Number:OM243126
OM243126
Discount Price
OM243126-100ul
1~2 Week
100ul
OM243126-50ul
50ul
1~2 Week
Product Profile
Product Name Cardiac Troponin I antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [3A10A12,5C3A7] to Cardiac Troponin ITroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to cTnI expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 3A10A12,5C3A7
Host Species Mouse
Tested Applications ELISAIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TNNC1
CMD2A
CTNI
CMH7
CMD1FF
TNNI3
RCM1
Target Cardiac Troponin I
Application

Application

Western blot analysis using anti-cTnI monoclonal antiobdy against truncated cTnI recombinant protein.

Application

Immunohistochemical analysis of paraffin-embedded human normal cardiac muscle tissue, showing cytoplasmic localization using anti-cTnI antibody with DAB staining.
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions Store at 4℃, for long term storage, store at -20℃.
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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