Mouse monoclonal [4C2] to cardiac Troponin ITroponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. It also binds to actin and tropomyosin.
Immunogen
epitope:23 – 29 a.a of human cardiac Troponin I
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
4C2
Host Species
Mouse
Tested Applications
PurifyELISAIAWB
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
reacts with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components (in the presence of 5 mM EDTA). Not affected by heparin, phosphorylation, oxidation and troponin complex formation. Does not cross-react with skeletal muscle troponin I.
Application Notes
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C.