Application
Western blot analysis of extracts from rat eye cells, using Caspase 1 (p20,Cleaved-Asn120) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | Caspase 1 (cleaved Asn120) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Caspase 1 (cleaved Asn120)Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 1. |
| Conjugation | Agarose |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | Cocktail |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMonkeyMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ICE CASP1 IL1BC P45 CASP1 (cleaved N120) CASP1 (cleaved Asn120) CASP1 cleaved N120 CASP1 cleaved Asn120 Cleaved CASP1 (N120) Cleaved CASP1 (Asn120) |
|---|---|
| Target | Caspase 1 (cleaved Asn120) |
| Molecular Weight(MW) | 18 kDa (note) |
| Tissue Specificity | Caspase 1 (p20,Cleaved-Asn120) Antibody detects endogenous levels of fragment of activated Caspase 1 resulting from cleavage adjacent to Asn120. |
Application
Western blot analysis of extracts from rat eye cells, using Caspase 1 (p20,Cleaved-Asn120) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:20000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
