Application
IHC image using - Detection of Caspase 1 by IHC in human placenta| Product Name | Caspase 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Caspase 1Caspase 1 (Interleukin 1 beta Converting Enzyme) is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Over-expression of Caspase 1 can induce apoptosis in fibroblast, which can be inhibited by over-expression of Crm A, a protein from pox virus. |
| Immunogen | A synthetic peptide from the second quarter of human Caspase 1 protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with all10 mM citrate buffer, pH 6.0 prior to immunostaining.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | 147678 IL1BC ICE P29466 P45 Caspase1 Caspase 1 834 CASP1 |
|---|---|
| Target | Caspase 1 |
| Tissue Specificity | This antibody reacts with the 45 kDa protein Caspase 1. |
| Cellular Localization | Cytoplasmic |
Application
IHC image using - Detection of Caspase 1 by IHC in human placenta| Positive Control | Placenta |
|---|---|
| Application Notes | IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with all10 mM citrate buffer, pH 6.0 prior to immunostaining.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4-8 °C. |
| Storage Buffer | PBS with sodium azide |
