Application
Western blot analysis of Capase-6 expression rat kidney tissue lysate. Both full length and the cleaved large fragment have been detected.| Product Name | Caspase 6 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Caspase 6The caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 6 is one of the major executioner caspases functioning in cellular apoptotic processes. Similar as other caspases, Caspase 6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with Caspase 3, Caspase 6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase 6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A. |
| Immunogen | Available on request. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB: Use at a concentration of 2-4 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Caspase 6 P55212 CASP6 MCH2 839 Caspase6 601532 |
|---|---|
| Target | Caspase 6 |
| Tissue Specificity | The antibody detects a 34 kDa procaspase-6 and the 22 kDa ckeaved fragnebt. The antibody specificity is confirmed by peptide inhibition studies. |
Application
Western blot analysis of Capase-6 expression rat kidney tissue lysate. Both full length and the cleaved large fragment have been detected.| Application Notes | WB: Use at a concentration of 2-4 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide |
