Application
Western Blot: Caspase 7 Antibody (Mch3 1-1-11) [ - HeLa whole cell lysate| Product Name | Caspase 7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal to human Caspase 7Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse. |
| Immunogen | Full-length recombinant human Caspase 7 protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ICELAP3 ICE-LAP3 CMH-1 CASP7 CMH1 601761 Caspase 7 840 Caspase7 P55210 MCH3 CMH 1 ICE LAP3 |
|---|---|
| Target | Caspase 7 |
| Tissue Specificity | Specific for Caspase 7. |
| Light Chain Type | kappa |
Application
Western Blot: Caspase 7 Antibody (Mch3 1-1-11) [ - HeLa whole cell lysate| Positive Control | HeLa and Jurkat whole cell extracts |
|---|---|
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Ascitic fluid with 0.1% sodium azide |
