| Product Name | Cathepsin K antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Cathepsin K (cathepsin K)The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Cathepsin K. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Rat, Dog, Pig, Rabbit, Rhesus Monkey, BovineHuman (100%), Mouse (88%), Rat (88%), Dog (91%), Pig (94%), Rabbit (90%), Rhesus Monkey (95%), Bovine (91%) |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CTS02 antibody CTSO antibody CTSO1 antibody CTSO2 antibody MGC23107 antibody PKND antibody PYCD antibody CTSK antibody cathepsin K antibody cathepsin O antibody cathepsin X antibody cathepsin O2 antibody cathepsin O1 antibody |
|---|---|
| Target | Cathepsin K |
| Molecular Weight(MW) | 37 kDa (note) |
| Cellular Localization | Lysosome |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
