Application
Western blot analysis of Cathepsin L expression with Jurkat cell lysate.| Product Name | Cathepsin L antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Cathepsin LCathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins suggests that it may play a role in invasion and metastasis and could be a useful prognostic indicator for cancer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
|
For WB: Use at a concentration of 0.5-4 µg/ml. : |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EC3.4.22.15 MEP CTSL1 CATL EC 3.4.22.15 CTSL |
|---|---|
| Target | Cathepsin L |
| Tissue Specificity | This antibody is specific for Cathepsin L. |
Application
Western blot analysis of Cathepsin L expression with Jurkat cell lysate.| Application Notes |
For WB: Use at a concentration of 0.5-4 µg/ml. : |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.1% BSA, 0.01% thimerosal |
