Application
IF analysis of Cav1.3 tested on human hippocampus lysates.| Product Name | Cav1.3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [S48A-9] to Cav1.3Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). |
| Immunogen | Fusion protein amino acids 859-875 of rat Cav1.3, accession numbr P27732 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | S48A-9 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIPWB |
| We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | CACNA1D voltage dependent L type calcium channel subunit alpha1D CACH3 voltage dependent L type calcium channel subunit alpha 1D CACN4 CACNL1A2 CACNA 1D |
|---|---|
| Target | Cav1.3 |
| Molecular Weight(MW) | 250kDa (note) |
| Tissue Specificity | No cross-reactivity against Cav1.2 |
| Light Chain Type | Kappa |
Application
IF analysis of Cav1.3 tested on human hippocampus lysates.| Application Notes | We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS pH7.4, 50% glycerol |
