Application
Western blot analysis of extracts from A549 cells, using CACNA1H Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | Cav3.2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Cav3.2Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1H gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CACNA1H. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Voltagedependent Ttype calcium channel subunit alpha1H Voltage-gated calcium channel subunit alpha Cav3.2 Low-voltage-activated calcium channel alpha1 3.2 subunit Voltagegated calcium channel subunit alpha Cav3.2 CACNA1H Lowvoltageactivated calcium ch |
|---|---|
| Target | Cav3.2 |
| Molecular Weight(MW) | 259 kDa (note) |
| Tissue Specificity | CACNA1H Antibody detects endogenous levels of total CACNA1H protein. |
Application
Western blot analysis of extracts from A549 cells, using CACNA1H Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
