Application
Immunofluorescence analysis of methanol-fixed A431, using CBL antibody at 1:50 dilution.Application
CBL antibody [C2C3], C-term detects CBL protein by Western blot analysis. A. 30 µg THP-1 whole cell lysate/extract 7.5 % SDS-PAGE CBL antibody [C2C3], C-term dilution: 1:1000| Product Name | CBL antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CBL (Cas-Br-M (murine) ecotropic retroviral transforming sequence)The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human CBL. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rhesus MonkeyMouse (84%), Rhesus Monkey (95%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | C-CBL antibody CBL2 antibody RNF55 antibody CBL antibody casitas B-lineage lymphoma proto-oncogene antibody E3 ubiquitin-protein ligase CBL antibody signal transduction protein CBL antibody proto-oncogene c-Cbl antibody oncogene CBL2 antibody RING |
|---|---|
| Molecular Weight(MW) | 100 kDa (note) |
| Cellular Localization | Cytoplasm |
Application
Immunofluorescence analysis of methanol-fixed A431, using CBL antibody at 1:50 dilution.
Application
CBL antibody [C2C3], C-term detects CBL protein by Western blot analysis. A. 30 µg THP-1 whole cell lysate/extract 7.5 % SDS-PAGE CBL antibody [C2C3], C-term dilution: 1:1000| Positive Control | THP-1 , *293T |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
