Application
CBLC antibody detects CBLC protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10 % SDS-PAGE, and the membrane was blotted with CBLC antibody at a dilution of 1:1000.| Product Name | CBLC antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CBLC (Cas-Br-M (murine) ecotropic retroviral transforming sequence c)CBL proteins, such as CBLC, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC (MIM 190090) homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling (Keane et al., 1999 [PubMed 10362357]).[supplied by OMIM] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CBLC. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, BovineHuman (100%), Rat (82%), Bovine (88%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CBL-3 antibody CBL-SL antibody RNF57 antibody CBLC antibody Cas-Br-M (murine) ectropic retroviral transforming sequence c antibody RING finger protein 57 antibody signal transduction protein CBL-C antibody SH3-binding protein CBL-C antibody SH3-bin |
|---|---|
| Target | CBLC |
| Molecular Weight(MW) | 52 kDa (note) (2) |
| Cellular Localization | Nucleus |
Application
CBLC antibody detects CBLC protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 10 % SDS-PAGE, and the membrane was blotted with CBLC antibody at a dilution of 1:1000.| Positive Control | mouse kidney |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
