Application
Immunofluorescence of CCDC106 in rat brain tissue with CCDC106 antibody at 20 μg/mL.Application
Western blot analysis of CCDC106 in human brain tissue lysate with CCDC106 antibody at (A) 0.5 and (B) 1 ug/ml.Application
Immunohistochemistry of CCDC106 in rat brain tissue with CCDC106 antibody at 5 ug/ml.| Product Name | CCDC106 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CCDC106The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ZNF581 Coiledcoil domain containing protein106 Coiled-coil domain containing protein 106 HSU79303 CCDC106 Coiledcoil domain containing protein 106 |
|---|---|
| Target | CCDC106 |
| Tissue Specificity | This antibody is specific for CCDC106 |
Application
Immunofluorescence of CCDC106 in rat brain tissue with CCDC106 antibody at 20 μg/mL.
Application
Western blot analysis of CCDC106 in human brain tissue lysate with CCDC106 antibody at (A) 0.5 and (B) 1 ug/ml.
Application
Immunohistochemistry of CCDC106 in rat brain tissue with CCDC106 antibody at 5 ug/ml.| Positive Control | Blocking Peptide: |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
