Application
Immunohistochemical analysis of paraffin-embedded human breast cancer, using CKR-2B antibody at 1:250 dilution.Application
CCR2 antibody [N1N2], N-term detects CCR2 protein at cytoplasm by immunofluorescent analysis. Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CCR2 protein stained by CCR2 antibody [N1N2], N-term diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm.| Product Name | CCR2 antibody , N-term |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CCR2 (chemokine (C-C motif) receptor 2)This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CCR2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Rhesus MonkeyRhesus Monkey (100%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CC-CKR-2 antibody CCR2A antibody CCR2B antibody CD192 antibody CKR2 antibody CKR2A antibody CKR2B antibody CMKBR2 antibody FLJ78302 antibody MCP-1-R antibody MGC103828 antibody MGC111760 antibody MGC168006 antibody CCR2 antibody CCR-2 antibod |
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| Molecular Weight(MW) | 42 kDa (note) |
| Cellular Localization | Cell membrane |
Application
Immunohistochemical analysis of paraffin-embedded human breast cancer, using CKR-2B antibody at 1:250 dilution.
Application
CCR2 antibody [N1N2], N-term detects CCR2 protein at cytoplasm by immunofluorescent analysis. Sample: Jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CCR2 protein stained by CCR2 antibody [N1N2], N-term diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
