Application
Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE diluted at 1:1000Application
CCR3 antibody [C2C3], C-term detects CCR3 protein at cytosol on human ovarian carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human ovarian carcinoma. CCR3 antibody [C2C3], C-term dilution: 1:500.Application
CCR3 antibody [C2C3], C-term detects CCR3 protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma. CCR3 antibody [C2C3], C-term dilution: 1:500.| Product Name | CCR3 antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CCR3 (chemokine (C-C motif) receptor 3)The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Rhesus MonkeyRhesus Monkey (93%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CC-CKR-3 antibody CD193 antibody CKR3 antibody CMKBR3 antibody MGC102841 antibody CCR3 antibody C-C CKR-3 antibody C-C chemokine receptor type 3 antibody eosinophil eotaxin receptor antibody CC chemokine receptor 3 antibody CCR-3 antibody eosino |
|---|---|
| Molecular Weight(MW) | 41 kDa (note) (4) |
| Cellular Localization | Cell membrane |
Application
Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE diluted at 1:1000
Application
CCR3 antibody [C2C3], C-term detects CCR3 protein at cytosol on human ovarian carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human ovarian carcinoma. CCR3 antibody [C2C3], C-term dilution: 1:500.
Application
CCR3 antibody [C2C3], C-term detects CCR3 protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma. CCR3 antibody [C2C3], C-term dilution: 1:500.| Positive Control | K562 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
