Application
Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 ug/mL.Application
Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 ug/mL.Application
Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 ug/ml.| Product Name | CCR7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CCR7The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
| Immunogen | CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | EBI1 chemokine (C-C motif) receptor 7 BLR2 CMKBR7 CCR-7 CD197 CDw197 CC-CKR-7 |
|---|---|
| Target | CCR7 |
| Tissue Specificity | CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins. |
Application
Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 ug/mL.
Application
Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 ug/mL.
Application
Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 ug/ml.| Application Notes | WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
