Immunohistochemical analysis of paraffin-embedded human breast ductal myoepithelium(A) and lymph tissue(B), showing cytoplasmic(A) and membrane(B) localization using anti-CD10 antibody with DAB staining(A) and AEC staining(B).
Mouse monoclonal antibody [2A1H5E1] to CD10This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not
Immunogen
The immunogen corresponding to human CD-10 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
2A1H5E1
Host Species
Mouse
Tested Applications
ELISAIHCIHC-P
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
SFE NEP MME CALLA
Target
CD10
Application
Application
Immunohistochemical analysis of paraffin-embedded human breast ductal myoepithelium(A) and lymph tissue(B), showing cytoplasmic(A) and membrane(B) localization using anti-CD10 antibody with DAB staining(A) and AEC staining(B).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.
Storage Buffer
Purified antibody in PBS containing 0.03% sodium azide.