Application
IHC-P analysis of human tonsil tissue using CD10 antibody [56C6].| Product Name | CD10 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [56C6] to CD10This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not |
| Immunogen | Recombinant human CD10 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 56C6 |
| Host Species | Mouse |
| Tested Applications | IHC-FIHC-P |
| Immunohistology - Frozen: Max Dilution 1/80: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SFE NEP MME membrane metallo-endopeptidase CALLA |
|---|---|
| Target | CD10 |
| Tissue Specificity | This antibody recognizes the human CD10 cell surface antigen. |
Application
IHC-P analysis of human tonsil tissue using CD10 antibody [56C6].| Application Notes | Immunohistology - Frozen: Max Dilution 1/80: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
