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CD10 antibody

Catalog Number:OM243906
OM243906
Discount Price
OM243906-100ul
1~2 Week
100ul
OM243906-50ul
50ul
1~2 Week
Product Profile
Product Name CD10 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [SN5c] to CD10This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not
Immunogen Partially purified cell membrane antigens from fresh leukemia cells.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number SN5c
Host Species Mouse
Tested Applications FACSIHC-FIPWB
FACS:1:200~1:500
IHC-F:1:50~1:100
IP:1:100~1:500
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms SFE
NEP
MME
membrane metallo-endopeptidase
CALLA
Target CD10
Tissue Specificity This antibody recognizes the human CD10 cell surface antigen.
Application

Application

FACS ImageStaining of human peripheral blood granulocytes with Mouse anti Human CD10:APC

Application

FACS ImageStaining of human peripheral blood granulocytes with Mouse anti Human CD10:Azide Free

Application

FACS ImageStaining of human peripheral blood granulocytes with Mouse anti Human CD10:Biotin

Application

FACS ImageStaining of human peripheral blood granulocytes with Mouse anti Human CD10:FITC
Application Notes FACS:1:200~1:500
IHC-F:1:50~1:100
IP:1:100~1:500
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Phosphate buffered saline containing 0.09% Sodium Azide
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