Mouse monoclonal antibody [SN6] to CD105This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Immunogen
Partially purified cell membrane antigens from fresh leukaemia cells.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
SN6
Host Species
Mouse
Tested Applications
FACSIHC-FIPWB
Flow Cytometry: Max Dilution 1/50 Optimal dilution / concentration should be determined by the end user.:
FACS analysis of KG1 cells using CD105 antibody [SN6].
Application Notes
Flow Cytometry: Max Dilution 1/50 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.