Application
FACS analysis of human peripheral blood lymphocytes using CD11a antibody [38].| Product Name | CD11a antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [38] to CD11aITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 38 |
| Host Species | Mouse |
| Tested Applications | BlockingFACSICC/IFIHC-FIPNeut |
| Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LFA1A LFA-1 CD11A ITGAL integrin alpha L (antigen CD11A (p180) lymphocyte function-associated antigen 1 alpha polypeptide) |
|---|---|
| Target | CD11a |
| Tissue Specificity | This antibody recognizes CD11a. |
Application
FACS analysis of human peripheral blood lymphocytes using CD11a antibody [38].| Application Notes | Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
