| Product Name | CD11b antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [3V29] to CD11bThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| Immunogen | The immunogen corresponding to a region within amino acids 17 and 1105 of human CD11b. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3V29 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-F |
| FC(1:500-2000)|IHC (frozen)(1:50-200): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MO1A MAC1A ITGAM CD11B MAC-1 CR3A integrin alpha M (complement component 3 receptor 3 subunit) SLEB6 |
|---|---|
| Target | CD11b |
| Tissue Specificity | This antibody was selected for its ability to detect human CD11b |
| Application Notes | FC(1:500-2000)|IHC (frozen)(1:50-200): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
