Application
IHC-Fr analysis of mouse lymph node using CD11b antibody [ICRF44] (Red), CD21 antibody [YTS105.18] (Green, ) and DAPI (blue).Application
IHC-Fr analysis of human spleen tissue using CD11b antibody [ICRF44].Application
IHC-Fr analysis of human tonsil tissue using CD11b antibody [ICRF44].| Product Name | CD11b antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [ICRF44] to CD11bThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | ICRF44 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FIP |
| Flow Cytometry: 1/10 - 1/100: |
|
| Species Reactivity | HumanBaboonRhesus MonkeyCynomolgus Monkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MO1A MAC1A ITGAM CD11B MAC-1 CR3A integrin alpha M (complement component 3 receptor 3 subunit) SLEB6 |
|---|---|
| Target | CD11b |
| Tissue Specificity | This antibody recognizes the human CD11b cell surface glycoprotein. |
Application
IHC-Fr analysis of mouse lymph node using CD11b antibody [ICRF44] (Red), CD21 antibody [YTS105.18] (Green, ) and DAPI (blue).
Application
IHC-Fr analysis of human spleen tissue using CD11b antibody [ICRF44].
Application
IHC-Fr analysis of human tonsil tissue using CD11b antibody [ICRF44].| Application Notes | Flow Cytometry: 1/10 - 1/100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
