| Product Name | CD11c antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [CBR-p150/4G1] to CD11cThis gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant human CD11c |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | CBR-p150/4G1 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FFunctional Assay |
| Immunohistology - Frozen: 5 - 10 ug/ml Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | SLEB6 ITGAX CD11C |
|---|---|
| Target | CD11C |
| Tissue Specificity | This antibody recognizes human CD11c. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. It does not recognize CD11a, CD11b or CD18. |
| Application Notes | Immunohistology - Frozen: 5 - 10 ug/ml Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline |
