| Product Name | CD14 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [61D3] to CD14CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. |
| Immunogen | The details of the immunogen for this antibody are not available. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 61D3 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FIP |
| Recommended dilutions: FACS: Use 1μg for 10^6 cells. IHC-Fr: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Monocyte Differentiation Antigen14 Monocyte Differentiation Antigen 14 CD14 molecule Monocyte differentiation antigen CD14 LPSR Lipopolysaccharide receptor CD14 antigen Myeloid cell specific leucine rich glycoprotein CD 14 CD14 |
|---|---|
| Target | CD14 |
| Tissue Specificity | Human CD14 |
| Cellular Localization | Cell Membrane |
| Application Notes | Recommended dilutions: FACS: Use 1μg for 10^6 cells. IHC-Fr: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Preservative: None Constituents: 100mM Borate. pH 8 |
