| Product Name | CD1a antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [BL 6] to CD1aThis gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | BL 6 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIHC-F |
| Recommended Starting Dilutions: For ICC/IF: Use at a concentration of 2 µg for 5x10 5 cells. For FACS: Use at a concentration of 2 µg for 5x10 5 cells. For IHC-F: Use at a dilution of 1:25 - 1:50. Optimal dilution should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD1 |
|---|---|
| Target | CD1a |
| Tissue Specificity | CD1a |
| Cellular Localization | Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. |
| Light Chain Type | kappa |
| Application Notes | Recommended Starting Dilutions: For ICC/IF: Use at a concentration of 2 µg for 5x10 5 cells. For FACS: Use at a concentration of 2 µg for 5x10 5 cells. For IHC-F: Use at a dilution of 1:25 - 1:50. Optimal dilution should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at –20°C. Avoid multiple freeze/thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
