| Product Name | CD23 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [2C23] to CD23The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| Immunogen | Human recombinant CD23 EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2C23 |
| Host Species | Mouse |
| Tested Applications | FACSNeutWB |
| Recommended Starting Dilutions: For WB: Use at a dilution of 1:500-1:1000. For FACS: Use at a dilution of 1:50-1:100. For Neutralization: functional assay was test in a functional ELISA. When 2 µg/mL (100 µL/well) of rhCD23/Fc epsilon RII is on ELISA plat, 2 µg/mL of GTX52617 could block 50% of the binding of 400 ng/mL of human IgE at 8 μg/mL, this antibody will block >90% of the binding. Optimal dilution should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CLEC4J Fc fragment of IgE low affinity II receptor for (CD23) FCER2 CD23A FCE2 BLAST-2 IGEBF |
|---|---|
| Target | CD23 |
| Tissue Specificity | This antibody was selected for its ability to detect human CD23 |
| Application Notes | Recommended Starting Dilutions: For WB: Use at a dilution of 1:500-1:1000. For FACS: Use at a dilution of 1:50-1:100. For Neutralization: functional assay was test in a functional ELISA. When 2 µg/mL (100 µL/well) of rhCD23/Fc epsilon RII is on ELISA plat, 2 µg/mL of GTX52617 could block 50% of the binding of 400 ng/mL of human IgE at 8 μg/mL, this antibody will block >90% of the binding. Optimal dilution should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
