Mouse monoclonal antibody [D3.6] to CD23The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Immunogen
Immunoprecipitated CD23 antigen from purified plasma membranes from EBV-transformed human lymphoblastoid B cell lines
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
D3.6
Host Species
Mouse
Tested Applications
FACS
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CLEC4J Fc fragment of IgE low affinity II receptor for (CD23) BLAST-2 FCER2 CD23A FCE2 IGEBF
Target
CD23
Tissue Specificity
This antibody recognizes CD23, a 45kDa cell surface glycoprotein that acts as a low affinity receptor for IgE.
Application
Application
FACS ImageStaining of human peripheral blood lymphocytes probed with Mouse anti Human CD23:RPE
Application
FACS ImageStaining of human peripheral blood lymphocytes with Mouse anti Human CD23:FITC
Application Notes
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.