| Product Name | CD239 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [BRIC221] to CD239This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | BRIC221 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSICC/IFIHC-FWB |
| FACS:1:200~1:500 ICC/IF:1:200~1:500 IHC-F:1:50~1:100 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BCAM AU basal cell adhesion molecule (Lutheran blood group) LU MSK19 |
|---|---|
| Target | CD239 |
| Tissue Specificity | This antibody recognizes an epitope in the fourth extracellular domain of CD239 (B-CAM). |
| Application Notes | FACS:1:200~1:500 ICC/IF:1:200~1:500 IHC-F:1:50~1:100 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | TRIS buffered glycine containing 0.09% Sodium Azide |
