Application
Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE diluted at 1:10000Application
Immunohistochemical analysis of paraffin-embedded human breast cancer, using CD27 antibody at 1:250 dilution.| Product Name | CD27 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CD27 (CD27 molecule)The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CD27. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MGC20393 antibody S152 antibody T14 antibody TNFRSF7 antibody Tp55 antibody CD27 antibody T-cell activation antigen CD27 antibody CD27 antigen antibody tumor necrosis factor receptor superfamily member 7 antibody T cell activation antigen S152 ant |
|---|---|
| Molecular Weight(MW) | 29 kDa (note) |
| Cellular Localization | Membrane |
Application
Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE diluted at 1:10000
Application
Immunohistochemical analysis of paraffin-embedded human breast cancer, using CD27 antibody at 1:250 dilution.| Positive Control | K562 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
