Application
FACS analysis of human peripheral blood lymphocytes using CD27 antibody [LT27] (Azide free).| Product Name | CD27 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [LT27] to CD27The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | LT27 |
| Host Species | Mouse |
| Tested Applications | FACSIP |
| Flow Cytometry: Max Dilution 1/100 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanSheepRhesus MonkeyCynomolgus Monkey |
| Concentration | 1mg/ml |
| Gene Synonyms | TNFRSF7 S152. LPFS2 S152 CD27 molecule Tp55 T14 |
|---|---|
| Target | CD27 |
| Tissue Specificity | This antibody recognizes human CD27. Clone LT27 precipitates a 55kDa protein under reducing conditions or a 120kDa protein under non-reducing conditions. |
Application
FACS analysis of human peripheral blood lymphocytes using CD27 antibody [LT27] (Azide free).| Application Notes | Flow Cytometry: Max Dilution 1/100 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline |
