Rabbit polyclonal to CD3 zetaCD3 consists of five invariant polypeptide chains that associate to form three dimmers: a heterodimer of gamma and epsilon chains, a heterodimer of delta and epsilon chains and a homodimer of two zeta chains or a heterodimer of zeta and eta chains. Zeta chain consists of three consecutive copies of the same motif. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.
Immunogen
Synthetic peptide: DGILFIYGVILTALFLRVK, corresponding to amino acids 36-54 of Human CD3 zeta.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
IHC-P: 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol with 10 mM Citrate buffer, pH 6.0. Optimal dilutions/concentrations should be determined by the end user.:
IHC-P analysis of human tonsil stained using CD3 zeta antibody.
Positive Control
Tonsil
Application Notes
IHC-P: 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol with 10 mM Citrate buffer, pH 6.0. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.