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CD3 zeta antibody

Catalog Number:OM244906
OM244906
Discount Price
OM244906-100ul
1~2 Week
100ul
OM244906-50ul
50ul
1~2 Week
Product Profile
Product Name CD3 zeta antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [G3] to CD3 zetaThe protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen 113 amino acid synthetic peptide corresponding to the cytoplasmic domain of murine zeta TCR subunit.
Key Feature
Clonality Monoclonal
Isotype IgG2a
Clone Number G3
Host Species Mouse
Tested Applications ELISAFACSIPWB
ELISA: Max Dilution 1 ug/ml:
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms CD247
CD247 molecule
CD3Q
CD3H
TCRZ
CD3Z
CD3-ZETA
T3Z
Target CD3 zeta
Tissue Specificity This antibody is specific for the TCR zeta chain subunit (CD247). The antibody is capable of precipitating both non-phosphorylated and tyrosine phosphorylated TCR zeta chain.
Application

Application

FACS ImageStaining of digitonin permeabilised lymphocytes with Mouse anti Human CD247 : FITC
Application Notes ELISA: Max Dilution 1 ug/ml:
Additional Information
Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Phosphate buffered saline containing 0.09% Sodium Azide
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