Mouse monoclonal [MEM - 05] to CD31CD31 antibodies are a superior marker for angiogenesis, when compared to Factor VIII and CD34 antibodies. CD31 has been used to measure angiogenesis in association with tumor recurrence. CD31 used in a panel with CD34 and Factor VIII has also been used to mark Kaposi's sarcoma and angiosarcomas. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
Immunogen
Tissue / cell preparation (Human). (Leucocytes of patient suffering from LGL-type leukaemia).
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MEM-05
Host Species
Mouse
Tested Applications
FACSWB
FACS: Use at an assay dependant concentration. WB: Use at an assay dependant dilution. Use under non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
173445 P16284 5175 PECAM-1 PECAM1 CD31 PECAM 1
Target
CD31
Tissue Specificity
This antibody reacts with CD31 antigen.
Application
Application
Surface staining of lysed and wash human peripheral blood with purified anti-human CD31 (detection by Goat anti-mouse IgG1: PE).
Application Notes
FACS: Use at an assay dependant concentration. WB: Use at an assay dependant dilution. Use under non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.