Mouse monoclonal antibody [SM0] to CD36The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgM
Clone Number
SMØ
Host Species
Mouse
Tested Applications
FACSIHC-FWBFunctional Assay
Flow Cytometry: 1/25 - 1/50 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GPIV FAT CHDS7 GP3B SCARB3 PASIV BDPLT10 GP4
Target
CD36
Tissue Specificity
This antibody recognizes the CD36 antigen. Clone SMØ is reported to block interaction of oxidised low-density lipoprotein (OXLDL) with CD36 (Sugihara et al.1992).
Application
Application
IHC-Fr analysis of human tonsil tissue using CD36 antibody [SMØ] (Azide free).
Application
FACS analysis of human peripheral blood monocytes using CD36 antibody [SMØ] (Azide free).
Application Notes
Flow Cytometry: 1/25 - 1/50 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20o only. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.