Mouse Monoclonal antibody [9H5A8] to CD4This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
Immunogen
Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9H5A8
Host Species
Mouse
Tested Applications
ELISAWB
WB: 0.5 - 1 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CD4 molecule CD4mut
Target
CD4
Application
Application
Western blot analysis of CD4 in human thymus tissue lysate with CD4 antibody at (A) 0.5 and (B) 1 μg/mL.