Application
IHC-Fr analysis of human tonsil tissue using CD4 antibody [RPA-T4].| Product Name | CD4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [RPA-T4] to CD4This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | RPA-T4 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-F |
| Flow Cytometry: 1/50 - 1/100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD4mut CD4 molecule |
|---|---|
| Target | CD4 |
| Tissue Specificity | This antibody recognizes human CD4. Clone RPA-T4 has been reported to block gp120-CD4 interaction (Piatier-Tonneau et al, 1997). |
Application
IHC-Fr analysis of human tonsil tissue using CD4 antibody [RPA-T4].| Application Notes | Flow Cytometry: 1/50 - 1/100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
