Application
IHC-Fr staining of a human tonsil with Mouse anti Human CD40 antibody, clone LOB7/6 , red in A and Mouse anti Human CD21 antibody, clone LB21 , green in B. The merged image is C with nuclei counter-stained blue using DAPI. Low powerApplication
IHC-Fr staining of a human tonsil with Mouse anti Human CD40 antibody, clone LOB7/6 , red in A and Mouse anti Human CD21 antibody, clone LB21 , green in B. The merged image is C with nuclei counter-stained blue using DAPI. High powerApplication
IHC-Fr staining of a human tonsil with Mouse anti Human CD40 antibody, clone LOB7/6 , red in A and Mouse anti Human CD21 antibody, clone LB21 , green in B. The merged image is C with nuclei counter-stained blue using DAPI. Medium powerApplication
IHC-Fr analysis of human tonsil tissue using CD40 antibody [LOB7/6] (Low endotoxin, azide free).| Product Name | CD40 antibody (Azide free) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [LOB7/6] to CD40The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | LOB7/6 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FIHC-PIP |
| Flow Cytometry: 1/100 - 1/200 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanDog |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CDW40 TNFRSF5 BP50 P50 |
|---|---|
| Target | CD40 |
| Tissue Specificity | This antibody recognizes the human CD40. |
Application
IHC-Fr staining of a human tonsil with Mouse anti Human CD40 antibody, clone LOB7/6 , red in A and Mouse anti Human CD21 antibody, clone LB21 , green in B. The merged image is C with nuclei counter-stained blue using DAPI. Low power
Application
IHC-Fr staining of a human tonsil with Mouse anti Human CD40 antibody, clone LOB7/6 , red in A and Mouse anti Human CD21 antibody, clone LB21 , green in B. The merged image is C with nuclei counter-stained blue using DAPI. High power
Application
IHC-Fr staining of a human tonsil with Mouse anti Human CD40 antibody, clone LOB7/6 , red in A and Mouse anti Human CD21 antibody, clone LB21 , green in B. The merged image is C with nuclei counter-stained blue using DAPI. Medium power
Application
IHC-Fr analysis of human tonsil tissue using CD40 antibody [LOB7/6] (Low endotoxin, azide free).| Application Notes | Flow Cytometry: 1/100 - 1/200 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Tris buffered saline |
