| Product Name | CD44 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [A3D8] to CD44Monoclonal Anti-Human CD44 recognizes the CD44 human cell surface glycoprotein. CD44 (PgP-1, ECM-III, HUTCH-1, Hermes antigens) is a transmembraneous 80-95 kDa glycoprotein with extensive O-linked glycosylation. The extracellular domain has 6 potential glycosylation sites. It is widely distributed on many tissues and in soluble form in plasma. It is a backbone molecule for the frequent In and the rare In group antigens which are expressed on a variety of peripheral blood and hematopoietic cells. CD44 molecules mediate a variety of functions: leukocyteendothelial cell binding, lymphocyte homing, extracellular matrix binding, enhancement of T cell activation and adhesion to monocytes. Monoclonal antibodies to CD44 are powerful tools in the analysis of these functions. The CD44 antigen is expressed on a variety of cell types including peripheral blood leukocytes (B and T lymphocytes, monocytes, granulocytes) and red cells. |
| Immunogen | GTX11358 is derived from the A3D8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with circulating malignant human Sezary T cells. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | A3D8 |
| Host Species | Mouse |
| Tested Applications | FACS |
| FACS: Use 5μl for 10^6 cells. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | LHR CDW44 CD44 107269 MUTCHI ECMR-III MGC10468 MDU2 Pgp1 ECMRIII IN MUTCH-I MDU3 MIC4 960 P16070 MC56 MUTCH I ECMR III |
|---|---|
| Target | CD44 |
| Application Notes | FACS: Use 5μl for 10^6 cells. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide; Constituents: 1% BSA, 0.01M PBS (pH7.4) |
