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CD44 antibody

Catalog Number:OM245365
OM245365
Discount Price
OM245365-100ul
1~2 Week
100ul
OM245365-50ul
50ul
1~2 Week
Product Profile
Product Name CD44 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [F10-44-2] to CD44The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Key Feature
Clonality Monoclonal
Isotype IgG2a
Clone Number F10-44-2
Host Species Mouse
Tested Applications FACSICC/IFIHC-FIHC-P
Flow Cytometry: 1/10 - 1/20:
Species Reactivity HumanCynomolgus Monkey
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms LHR
HUTCH-I
CDW44
ECMR-III
MDU2
CSPG8
Pgp1
IN
MIC4
MDU3
MC56
CD44 molecule (Indian blood group)
HCELL
Target CD44
Tissue Specificity This antibody recognizes an epitope on human CD44 outside the regions coded for by the variable region exons and is thus expected to recognize all isoforms of human CD44 (Mackay et al. 1994).
Application

Application

FACS analysis of human peripheral blood lymphocytes using CD44 antibody [F10-44-2].

Application

IHC-P analysis of human breast cancer biopsy tissue using CD44 antibody [F10-44-2].
Application Notes Flow Cytometry: 1/10 - 1/20:
Additional Information
Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Phosphate buffered saline containing 0.09% Sodium Azide
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