| Product Name | CD44v7/8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [VFF-17] to CD44v7/8The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | VFF-17 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-FIHC-PWB |
| Flow Cytometry: 1/10 - 1/100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LHR HUTCH-I CDW44 CD44 ECMR-III MDU2 CSPG8 Pgp1 IN MIC4 MDU3 MC56 CD44 molecule (Indian blood group) HCELL |
|---|---|
| Target | CD44v7/8 |
| Tissue Specificity | This antibody recognizes an epitope encoded by exons v7-v8 on the variant portion of human CD44. |
| Application Notes | Flow Cytometry: 1/10 - 1/100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline |
