Application
Western blot analysis using anti-CD45 monoclonal antibody against truncated CD45 recombinant protein(1).Application
Immunohistochemical analysis of paraffin-embedded human lymph node tissue,showing membrane and cytoplasmic localization with DAB staining using anti-CD45 Antibody.| Product Name | CD45 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4A8A4C7A2] to CD45The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] |
| Immunogen | The immunogen corresponding to CD45 expressed in E. Coli. |
| Conjugation | Agarose |
| Modification | Acetylated |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4A8A4C7A2 |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LY5 PTPRC GP180 CD45R T200 L-CA LCA B220 |
|---|---|
| Target | CD45 |
| Cellular Localization | Colocalized with DPP4 in membrane rafts. |
Application
Western blot analysis using anti-CD45 monoclonal antibody against truncated CD45 recombinant protein(1).
Application
Immunohistochemical analysis of paraffin-embedded human lymph node tissue,showing membrane and cytoplasmic localization with DAB staining using anti-CD45 Antibody.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
