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CD45 antibody

Catalog Number:OM245421
OM245421
Discount Price
OM245421-100ul
1~2 Week
100ul
OM245421-50ul
50ul
1~2 Week
Product Profile
Product Name CD45 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [F10-89-4] to CD45The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Key Feature
Clonality Monoclonal
Isotype IgG2a
Clone Number F10-89-4
Host Species Mouse
Tested Applications FACSIHC-FIHC-PIP
Flow Cytometry: 1/10 - 1/50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms LY5
T200
L-CA
PTPRC
LCA
CD45R
protein tyrosine phosphatase
receptor type
C
B220
GP180
Target CD45
Tissue Specificity This antibody reacts with all forms of CD45.
Application

Application

FACS ImageStaining of human peripheral blood lymphocytes with Mouse anti Human CD45:RPE

Application

FACS ImageStaining of human peripheral blood lymphocytes with Mouse anti Human CD45:FITC

Application

FACS ImageStaining of human peripheral blood lymphocytes with Mouse anti Human CD45:Biotin

Application

FACS ImageStaining of human peripheral blood lymphocytes with Mouse anti Human CD45:APC
Application Notes Flow Cytometry: 1/10 - 1/50:
Additional Information
Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Phosphate buffered saline containing 0.09% Sodium Azide
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