Mouse monoclonal [MEM - 43] to CD59CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.
Immunogen
Thymocytes and T lymphocytes.
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
MEM-43
Host Species
Mouse
Tested Applications
FACSIPWB
FACS: Use at an assay dependant concentration. FuncS: Use at an assay dependant dilution. MEM-43 inhibits the complement-protecting activity of CD59. IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use under non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
CD59 antigen (human). MEM-43 identified CD59 as the new cluster on 4th HLDA Workshop. MEM-43 reacts with well defined epitope (WhO, P-53).
Cellular Localization
Cell Membrane
Application
Application
Surface staining of human peripheral blood cells with anti-human CD59: PE .
Application Notes
FACS: Use at an assay dependant concentration. FuncS: Use at an assay dependant dilution. MEM-43 inhibits the complement-protecting activity of CD59. IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use under non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.