Rabbit Polyclonal antibody to CD62EThe protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human SELE
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ELAM ESEL selectin E ELAM1 SELE LECAM2
Target
CD62E
Molecular Weight(MW)
67 KDa (note)
Application
Application
WB analysis of extracts from various cells using CD62E antibody.
Application
ICC/IF analysis of MCF-7 cells using CD62E antibody (green) and DAPI (blue).
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.